Faculty & Staff

Post Doctoral Fellows

Klazina Kooiman, PhD

Visiting Scholar, UPMC Heart and Vascular Institute



 

 

 

 

 

 

Peer Reviewed Articles

  1. Florea BI, van der Sandt IC, Schrier SM, Kooiman K, Deryckere K, de Boer AG, Junginger HE, Borchard G. Evidence of P-glycoprotein mediated apical to basolateral transport of flunisolide in human broncho-tracheal epithelial cells (Calu-3). Br J Pharmacol 2001;134:1555-1563.
  2. van Wamel A, Kooiman K, Harteveld M, Emmer M, ten Cate FJ, Versluis M, de Jong N. Vibrating microbubbles poking individual cells: drug transfer into cells via sonoporation. J Control Release 2006;112:149-155.
  3. Juffermans LJ, Meijering DB, van Wamel A, Henning RH, Kooiman K, Emmer M, de Jong N, van Gilst WH, Musters R, Paulus WJ, van Rossum AC, Deelman LE, Kamp O. Ultrasound and microbubble-targeted delivery of therapeutic compounds: ICIN Report Project 49: Drug and gene delivery through ultrasound and microbubbles. Neth Heart J 2009;17:82-86.
  4. Meijering BD, Juffermans LJ, van Wamel A, Henning RH, Zuhorn IS, Emmer M, Versteilen AM, Paulus WJ, van Gilst WH, Kooiman K, de Jong N, Musters RJ, Deelman LE, Kamp O. Ultrasound and microbubble-targeted delivery of macromolecules is regulated by induction of endocytosis and pore formation. Circ Res 2009;104:679-687.
  5. Kooiman K, Bohmer MR, Emmer M, Vos HJ, Chlon C, Shi WT, Hall CS, de Winter SH, Schroen K, Versluis M, de Jong N, van Wamel A. Oil-filled polymer microcapsules for ultrasound-mediated delivery of lipophilic drugs. J Control Release 2009;133:109-118.
  6. Kooiman K, Emmer M, Foppen-Harteveld M, van Wamel A, de Jong N. Increasing the endothelial layer permeability through ultrasound-activated microbubbles. IEEE Trans Biomed Eng 2010;57:29-32.
  7. Kooiman K, Foppen-Harteveld M, van der Steen AF, de Jong N. Sonoporation of endothelial cells by vibrating targeted microbubbles. J Control Release 2011;154:35-41.
  8. Faez T, Skachkov I, Versluis M, Kooiman K, de Jong N. In vivo characterization of ultrasound contrast agents: microbubble spectroscopy in a chicken embryo. Ultrasound Med Biol 2012;38:1608-1607.
  9. Faez T, Emmer M, Kooiman K, Versluis M, van der Steen A, de Jong N. 20 years of ultrasound contrast agent modeling. IEEE Trans Ultrason Ferroelectr Freq Control 2013;60:7-20.
  10. Kokhuis TJ, Garbin V, Kooiman K, Naaijkens BA, Juffermans LJ, Kamp O, van der Steen AF, Versluis M, de Jong N. Secondary bjerknes forces deform targeted microbubbles. Ultrasound Med Biol 2013;39:490-506.
  11. Ten Cate DF, Luime JJ, van der Ven M, Hazes JM, Kooiman K, de Jong N, Bosch JG. Very different performance of the power Doppler modalities of several ultrasound machines ascertained by a microvessel flow phantom. Arthritis Res Ther 2013;15:R162.
  12. Kooiman K, van der Steen AF, de Jong N. Role of intracellular calcium and reactive oxygen species in microbubble-mediated alterations of endothelial layer permeability. IEEE Trans Ultrason Ferroelectr Freq Control 2013;60:1811-1815.
  13. Kooiman K, Vos HJ, Versluis M, de Jong N. Acoustic behavior of microbubbles and implications for drug delivery. Adv Drug Deliv Rev 2014;72:28-48.
  14. Kooiman K, Kokhuis TJA, van Rooij T, Skachkov I, Nigg A, Bosch JG, van der Steen AFW, van Cappellen WA, de Jong N. DSPC or DPPC as main shell component influences ligand distribution and binding area of lipid-coated targeted microbubbles. Eur J Lipid Sci Technol 2014:116:1217-1227.
  15. Skachkov I, Luan Y, van der Steen AF, de Jong N, Kooiman K. Targeted microbubble mediated sonoporation of endothelial cells in vivo. IEEE Trans Ultrason Ferroelectr Freq Control 2014;61:1661-1667.
  16. Kokhuis TJ, Skachkov I, Naaijkens BA, Juffermans LJ, Kamp O, Kooiman K, van der Steen AF, Versluis M, de Jong N. Intravital microscopy of localized stem cell delivery using microbubbles and acoustic radiation force. Biotechnol Bioeng 2015;112:220-227.
  17. Bernsen MR, Kooiman K, Segbers M, van Leeuwen FW, de Jong M. Biomarkers in preclinical cancer imaging. Eur J Nucl Med Mol Imaging 2015;42:579-596.
  18. Raymond JL, Luan Y, van Rooij T, Kooiman K, Huang SL, McPherson DD, Versluis M, de Jong N, Holland CK. Impulse response method for characterization of echogenic liposomes. J Acoust Soc Am 2015;137:1693-1703.
  19. van Rooij T, Daeichin V, Skachkov I, de Jong N, Kooiman K. Targeted ultrasound contrast agents for ultrasound molecular imaging and therapy. Int J Hyperthermia 2015;31:90-106.
  20. van Rooij T, Luan Y, Renaud G, van der Steen AF, Versluis M, de Jong N, Kooiman K. Non-linear response and viscoelastic properties of lipid-coated microbubbles: DSPC versus DPPC. Ultrasound Med Biol 2015;41:1432-1445.
  21. Daeichin V, Akkus Z, Skachkov I, Kooiman K, Needles A, Sluimer J, Janssen B, Daemen MJ, van der Steen AF, de Jong N, Bosch JG. Quantification of bound microbubbles in ultrasound molecular imaging. IEEE Trans Ultrason Ferroelectr Freq Control 2015;62:1190-1200.