Faculty & Staff
Soheb Anwar Mohammed, PhD
Research Assistant Professor
University of Pittsburgh School of Medicine (Cardiology), Vascular Medicine Institute
Peer Reviewed Articles
1. Adela R, Mohammed SA, Kanwal A, Vishwakarma G, Reddy PNC, Banerjee SK. Elevated levels of GDF15 is associated with increased angiotensin II in hypertensive patients with Type 2 diabetes. Personalized Medicine 2016;13(40):325-336. https://doi.org/10.2217/pme-2016-0030.
2. Mohammed RS, Bagul PK, Katare PB, Mohammed SA, Padiya R, Banerjee SK. Garlic activates SIRT-3 to prevent cardiac oxidative stress and mitochondrial dysfunction in diabetes. Life Sciences 2016;164:42-51. https://doi.org/10.1016/j.lfs.2016.08.030.
3. Meghwani H, Prabhakar P, Mohammed SA, Seth S, Hote MP, Banerjee SK, Arava SK, Ray R, Maulik SK. Beneficial effects of aqueous extract of stem bark of Terminalia arjuna (Roxb.), An ayurvedic drug in experimental pulmonary hypertension. Journal of Ethnopharmacology 2017;197:184-194. https://doi.org/10.1016/j.jep.2016.07.029.
4. Khatua, TN, Borkar RM, Mohammed SA, Dinda AK, Ragampeta S , Banerjee SK. Novel sulfur metabolites of garlic attenuate cardiac hypertrophy and remodeling through induction of Na+/K+-ATPase expression. Frontiers in Pharmacology 2017;8:18. https://doi.org/10.3389/fphar.2017.00018.
5. Himanshu M, Prabhakar P, Mohammed SA, Dua P, Seth S, Hote MP, Banerjee SK, Arava SK, Ray R, Maulik SK. The beneficial effect of Ocimum sanctum (Linn) against monocrotaline-induced pulmonary hypertension in rats. Medicines 2018;5(2):34. https://doi.org/10.3390/medicines5020034.
6. Palak G, Prabhakar P, Meghwani H, Mohammed SA, Banerjee SK, Seth S, Hote MP, Reeta KH, Ray R, Maulik SK. Beneficial effects of fenofibrate in pulmonary hypertension in rats. Molecular and Cellular Biochemistry 2018;449(1):185194. https://doi.org/10.1007/s11010-018-3355-3.
7. Mohammed SA, Paramesha B, Kumar Y, Tariq U, Arava SK, Banerjee SK. Allylmethylsulfide, a sulfur compound derived from garlic, attenuates isoproterenol-induced cardiac hypertrophy in rats. Oxidative Medicine and Cellular Longevity 2020;7856318. https://doi.org/10.1155/2020/7856318.
8. Borkar RM, Gajji S, Mohammed SA, Srivastava M, Reddy VG, Jala A, Asthana S, Kamal A, Banerjee SK, Ragampeta S. Identification and characterization of in vitro and in vivo fidarestat metabolites: Toxicity and efficacy evaluation of metabolites. Journal of Mass Spectrometry 2021;56(2):4694. https://doi.org/10.1002/jms.4694.
9. Mohammed SA, Bugga P, Meghwani H, Reddy MPK, Arava SK, Banerjee SK. Allyl Methyl Sulfide Preserved Pressure Overload-Induced Heart Failure Via Modulation of Mitochondrial Function. Biomedicine & Pharmacotherapy 2021;138:111316. https://doi.org/10.1016/j.biopha.2021.111316.
10. Paramesha B, Mohammed SA, Meghwani H, Maulik SK, Arava SK, Banerjee SK. Sirt1 and Sirt3 Activation Improved Cardiac Function of Diabetic Rats via Modulation of Mitochondrial Function. Antioxidants 2021;10(3):338. https://doi.org/10.3390/antiox10030338.
11. Alam MJ, Uppulapu SK, Varghese B, Mohammed SA, Adela R, Arava SK, Banerjee SK. Pregestational Diabetes Alters Cardiac Structure and Function of Neonatal Rats Through Developmental Plasticity. Frontiers in Cardiovascular Medicine 2022;9:919293. https://doi.org/10.3389/fcvm.2022.919293.
12. Ahmad SP, Mohammed SA, Gupta S, Das A, Meghwani H, Maulik SK, Banerjee SK, Kumar A. Oxygen releasing and antioxidant breathing cardiac patch delivering exosomes promotes heart repair after myocardial infarction. Chemical Engineering Journal 2022;248:132490. https://doi.org/10.1016/j.cej.2021.132490.
13. Paramesha B, Mohammed SA, Meghwani H, Maulik SK, Arava SK, Banerjee SK. Empagliflozin prohibits high fructose diet-induced cardiac dysfunction in rats via attenuation of mitochondria-driven oxidative stress. Life Sciences 2022; 307:120862. https://doi.org/10.1016/j.lfs.2022.120862.
14. Yu FTH, Amjad MW, Mohammed SA, Yu GY, Chen X, Pacella JJ. The effect of ultrasound pulse length on sonoreperfusion therapy. Ultrasound in Medicine and Biology 2023;49(1):152-164. https://doi.org/10.1016/j.ultrasmedbio.2022.08.009.
15. Paramesha B, Mohammed SA, Alam MJ, Katare P, Meghwani H, Maulik SK, Arava S, Banerjee SK. Empagliflozin prohibits high-fructose diet-induced cardiac dysfunction in rats via attenuation of mitochondria-driven oxidative stress. Life Sciences 2022;307(15):120862. https://doi.org/10.1016/j.lfs.2022.120862.
16. Mohammed SA, Editorial: Left, but not right, ventricular status determines heart failure in adults with Ebstein anomaly - A case-control study based on magnetic resonance, Int J Cardiol 2022;361:38–39. https://doi.org/10.1016/j.ijcard.2022.05.037.
17. Mohammed SA, Amjad MW, Acosta MF, Chen X, Lavery L, Hanrahan D, Unger EC, Meuillet EJ, Pacella JJ. Fibrin-targeted phase shift microbubbles for the treatment of microvascular obstruction. Nanotheranostics 2024;8(1):33-47. doi: 10.7150/ntno.85092.
18. Cortes DRE, Szurszewski TB, Hartwick S, Amjad MW, Mohammed SA, Chen X, Pacella JJ, Christodoulou AG, Wu YL. Non-invasive Free-breathing Gating-free Extracellular Cellular Volume Quantification for Repetitive Myocardial Fibrosis Evaluation in Rodents. bioRxiv 2025;07(11):664411. doi: https://doi.org/10.1101/2025.07.11.664411.
Abstracts and Presentations
1. Bahare S, Zucca P, Orhan IE, Azzini E, Adetunji CO, Mohammed SA, Banerjee SK et al. Allicin and health: A comprehensive review. Trends in Food Science & Technology 2019;86:502-516. https://doi.org/10.1016/j.tifs.2019.03.003.
2. Mohammed SA, Chen X, Acosta MF, Hanrahan D, Unger EC, Meuillet EJ, Pacella JJ. Abstract 14089: Phase Shift Microbubbles for the Treatment of Microvascular Obstruction. Circulation 2021;144:14089–14089. https://doi.org/10.1161/circ.144.suppl_1.14089.
3. Mohammed SA, Romeo J, Gawalt E, Lovelace T, Pacella, JJ. TCT-208 A Novel Vascular Scaffold for Focal Delivery of Antiplatelet Therapy. Journal of American College of Cardiology 2021;78:85–85. https://doi.org/10.1016/j.jacc.2021.09.1061.
4. Mohammed SA, Amjad MW, Chen X, Acosta MF, Hanrahan D, Unger EC, Meuillet EJ, Pacella JJ. Fibrin-Targeted Phase Shift Microbubbles Outperformed Fibrin-Targeted Microbubbles in Microvascular Obstruction Treatment. 27th European Symposium on Ultrasound Contrast Imaging, January 20-21, 2022.
5. Amjad MW, Mohammed SA, Chen X, Matsunaga TO, Freeman BA, Fazzari M, Pacella JJDevelopment and Characterization of Nitro-Fatty Acid Microbubbles (NFABs) for the Treatment of Microvascular Obstruction. The 27th European symposium on Ultrasound Contrast Imaging, January 20-21, 2022.
6. Mohammed SA, Amjad MW, Chen X, Acosta MF, Hanrahan D, Unger EC, Meuillet EJ, Pacella JJ. Fibrin targeted phase shift microbubbles for the treatment of microvascular obstruction. Journal of American College of Cardiology 2022;79:1783–1783. https://doi.org/10.1016/S0735-1097(22)02774-7.
7. Mohammed SA, Amjad MW, Chen X, Acosta MF, Hanrahan D, Unger EC, Meuillet EJ, Pacella JJ. Fibrin-Targeted Phase Shift Microbubbles Outperform Fibrin-Targeted Microbubbles for the Treatment of Microvascular Obstruction. Circulation 2022:146;A15543. https://www.ahajournals.org/doi/10.1161/circ.146.suppl_1.15543.
8. Romeo J, Mohammed SA, Pacella JJ, Gawalt E. TCT-135 Ticagrelor Coated Stent to Eliminate the Need for Anti Platelet Therapy Post PCI. J Am Coll Cardiol 2022 Sept;82(17_Supp):B66-7.
9. Romeo J, Mohammed SA, Pacella JJ, Gawalt E. TCT-165 A Novel Ticagrelor Coated Stent to Eliminate the Need for DAPT after PCI. J Am Coll Cardiol 2023;82(Supplement):B52-B53.
10. Yu FTH, Amjad MW, Mohammed SA, Yu GZ, Chen X, Pacella JJ. The Effect of Increasing the Ultrasound Pulse Length on Sonoreperfusion Therapy. Circ 2022;146:A14673. https://doi.org/10.1161/circ.146.suppl_1.14673.
11. Amjad MW, Mohammed SA, Fazzari M, Chen X, Freeman B, Matsunaga T, Pacella JJ. Cardioprotective efficacy of ultrasound-targeted Nitrofatty acid microbubbles in Rat Myocardial Ischemia-Reperfusion Injury Model. J Acoust Soc Am 2023;153:A102. https://doi.org/10.1121/10.0018308.
12. Mohammed SA, Amjad MW, Chen X, Acosta M, Hanrahan D, Meuillet E, Unger E, Pacella JJ. Sonoreperfusion with Fibrin-Targeted Phase Shift Microbubbles for the Treatment of Microvascular Obstruction. J Acoust Soc Am 2023;153:A141. https://doi.org/10.1121/10.0018436.
13. Amjad MW, Mohammed SA, Chen X, Villanueva FS, Pacella JJ. Ultrasound Targeted Microbubble Cavitation (UTMC) for the treatment of Myocardial Microvascular Obstruction (MVO). J Acoust Soc Am 2024;155(3_Supplement):A188-A. https://doi.org/10.1121/10.0027265.
14. Amjad MW, Mohammed SA, Chen X, Villanueva FS, Pacella JJ. Ultrasound-targeted microbubble cavitation for the treatment of myocardial microvascular obstruction: a porcine study. Circ 2024;150 (Suppl_1):A4146203. AHA Scientific Sessions November 2024, Chicago, IL. https://doi.org/10.1161/circ.150.suppl_1.4146203.
15. Mohammed SA, Amjad MW, Romeo J, Harris K, Ellen Gawalt E, Pacella JJ. Focal Delivery of Antiplatelet Therapy to Prevent Post-Stent Bleeding in High-Risk Patients. Circ 2024;150 (Suppl_1):A4134630. AHA Scientific Sessions November 2024, Chicago, IL. https://doi.org/10.1161/circ.150.suppl_1.4134630.
16. Amjad MW, Mohammed SA, Fazzari M, Chen X, Freeman BA, Matsunaga TO, Pacella JJ. Ultrasound Targeted Nitrofatty Acid Microbubbles (NFABs) Mitigate the Progression of Myocardial Fibrosis. The 29th European Symposium on Ultrasound Contrast Imaging, 16-17 January 2025.
17. Mohammed SA, Amjad MW, Chen X, Unger EC, Meuillet EJ, Pacella JJ. Sonoreperfusion with Fibrin-Targeted Phase Shift Microbubbles for the Treatment of Microvascular Obstruction. The 36th Annual American Society of Echocardiography, September 7th, 2025, Nashville, TN.
18. Mohammed SA, Amjad MW, Chen X, Unger EC, Meuillet EJ, Pacella JJ. Sonoreperfusion with Fibrin-Targeted Phase Shift Microbubbles for the Treatment of Microvascular Obstruction: A Porcine Study. Advances in Contrast Ultrasound: 39th International Bubble Conference, September 10th, 2025, Chicago, IL.
