Faculty & Staff

Post Doctoral Fellows

Geetika Wadhwa, PhD

Postdoctoral Associate, University of Pittsburgh School of Medicine (Cardiology), UPMC Heart and Vascular Institute, Vascular Medicine Institute




 


Peer Reviewed Articles

1.  Wadhwa G, Krishna KV, Dubey SK, Taliyan R. Design and biological evaluation of Repaglinide loaded polymeric nanocarriers for diabetes linked neurodegenerative disorder: QbD-driven optimization, in situ, in vitro, and in vivo investigation. Int J Pharm 2023 Apr 5:636:122824.

2.  Wadhwa G, Krishna KV, Dubey SK, Taliyan R. PEGylated Polymer–Lipid Hybrid Nanoparticles to Enhance In Vivo Exposure and Uptake of Repaglinide in Brain Cells to Treat Diabetes-Linked Neurodegenerative Disorders. ACS Applied Nano Materials 2023 Feb 8;6(5):3497-3512.

3.  Wadhwa G, Krishna KV, Taliyan R, Tandon N, Yadav SS, Banerjee D, et al. A novel UPLC–MS/MS method for simultaneous quantification of trigonelline, 4-hydroxy isoleucine, and diosgenin from Trigonella foenum-graecum extract: Application to pharmacokinetic study in healthy and type 2 diabetic rats. Biomed Chromatogr 2022 Feb 1;36(2):e5275.

4.  Wadhwa G, Krishna KV, Dubey SK, Taliyan R. Development and validation of RP-HPLC method for quantification of repaglinide in mPEG-PCL polymeric nanoparticles: QbD-driven optimization, force degradation study, and assessment of in vitro release mathematic modeling. Microchem J 2021 Sep 1;168:106491.

5.  Wadhwa G, Krishna KV, Taliyan R, et al. Preclinical pharmacokinetics of trigonelline using ultra-performance liquid chromatography–tandem mass spectrometry and pharmacological studies targeting type 2 diabetes. Sep Sci Plus 2021 Apr 1;4(4):185.

6.  Wadhwa G, Krishna KV, Taliyan R, Tandon N, et al. Preclinical pharmacokinetic and pharmacodynamic modelling study of 4-hydroxy isoleucine using validated ultra-performance liquid chromatography-tandem mass spectrometry. RSC Adv 2020 Feb;10(10):5525–32.

7.  Wadhwa G, Kumar S, Mittal V, Rao R. Encapsulation of babchi essential oil into microsponges: Physicochemical properties, cytotoxic evaluation and anti-microbial activity. J Food Drug Anal 2019 Jan 1;27(1):60–70.

8.  Wadhwa G, Kumar S, Chhabra L, Mahant S, Rao R. Essential oil–cyclodextrin complexes: an updated review. J Incl Phenom Macrocycl Chem 2017 Aug 21;89(1):39–58.

9. Gorantla S,  Wadhwa G, Jain S, Sankar S, Kshitij Nuwal, Mahmood A, et al. Recent advances in nanocarriers for nutrient delivery. Drug Deliv Transl Res 2021;1:3.

10. Pradhan R, Krishna KV,  Wadhwa G, Taliyan R, et al. QbD-driven development and validation of HPLC method for determination of Bisphenol A and Bis-sulphone in environmental samples. Int J Environ Anal Chem 2020 Jan 2;100(1):42–54.

11. Krishna KV,  Wadhwa G, Alexander A, Kanojia N, Saha RN, Kukreti R, et al. Design and Biological Evaluation of Lipoprotein-Based Donepezil Nanocarrier for Enhanced Brain Uptake through Oral Delivery. ACS Chem Neurosci 2019 Sep;10(9):4124–35.

 

Abstracts and Presentations

1.  Wadhwa G, Dubey SK, Taliyan R. Repaglinide Loaded Hybrid Nanocarrier for the Management of Diabetes Mellitus Induced Neuronal Complications. AAIC Neuroscience Next. November, 2020.

2.  Wadhwa G, Dubey SK, Taliyan R. Preclinical Investigation of Developed Lipid Hybrid Nanocarrier for the Treatment of Diabetes Induce Neuronal Complications, Presented at Annual conference of Society for the study of Xenobiotics (SSX), India. July 2021.

3.  Wadhwa G, Dubey SK, Taliyan R, In vitro Release Study of Insulinotropic Agent for the Treatment of Diabetes Induce Neuronal Complications, Presented at Dissolution Research Presentation India (DRPI), India. June 2021.

4.  Wadhwa G, Taliyan R. Preclinical investigation of Repaglinide Nanoparticles in High Fat Diet with Streptozotocin-Induced Memory Impaired Rats. Alzheimer’s Association International Conference. July 2022.

5.  Wadhwa G, Taliyan R. Oral Delivery of Insulinotropic Agent Loaded Nanocarrier to Enhanced Brain Uptake for Diabetes Linked Neurodegenerative Disorder in Wistar Rats. Presented at International Symposium on Recent Trends and future opportunities in pharmaceuticals-NIPER Pharmacon, India. November 2022.

6.  Wadhwa G, Taliyan R. Development of PEGylated Hybrid Nanocarrier for the treatment of Diabetes induced neuronal complications. Presented at 20th international e-symposium by control released society (CRS India chapter). February 2022.

7.  Wadhwa G, Taliyan R. Mechanistic Insights of Meglitinides Drug Repurposing and Delivery to Brain for Metabolic Syndrome Linked Neurodegenerative Disease. Alzheimer’s Association International Conference. July 2023.