Faculty & Staff
Anurag N. Paranjape, PhD
Research Instructor
University of Pittsburgh School of Medicine (Cardiology), Vascular Medicine Institute
Peer Reviewed Articles
1. Dey D, et al. Phenotypic and functional characterization of human mammary stem/progenitor cells in long term culture. PLoS One 2009;4: e5329. doi:10.1371/journal.pone.0005329.
2. Paranjape AN , et al. Introduction of SV40ER and hTERT into mammospheres generates breast cancer cells with stem cell properties. Oncogene 2012;31:1896-1909. doi:10.1038/onc.2011.378.
3. Sharma A, Paranjape ANRangarajan A, Dighe RR. A Monoclonal Antibody against Human Notch1 Ligand–Binding Domain Depletes Subpopulation of Putative Breast Cancer Stem–like Cells. Molecular Cancer Therapeutics 2012;11:77-86. doi:10.1158/1535-7163.Mct-11-0508.
4. Paranjape AN , et al. Bmi1 regulates self-renewal and epithelial to mesenchymal transition in breast cancer cells through Nanog. BMC Cancer 2014;14:785. doi:10.1186/1471-2407-14-785.
5. Mallampati S, et al. Tyrosine kinase inhibitors induce mesenchymal stem cell-mediated resistance in BCR-ABL+ acute lymphoblastic leukemia. Blood 2015;125:2968-2973. doi:10.1182/blood-2014-05-576421.
6. Soundararajan R, Paranjape AN, Barsan V, Chang JT, Mani SA. A novel embryonic plasticity gene signature that predicts metastatic competence and clinical outcome. Sci Rep 2015;5:11766, doi:10.1038/srep11766.
7. Paranjape AN , et al. Inhibition of FOXC2 restores epithelial phenotype and drug sensitivity in prostate cancer cells with stem-cell properties. Oncogene 2016;35:5963-5976. doi:10.1038/onc.2015.498.
8. Werden SJ, Paranjape AN, et al. Phosphorylation of serine 367 of FOXC2 by p38 regulates ZEB1 and breast cancer metastasis, without impacting primary tumor growth. Oncogene 2016;35:5977-5988. doi:10.1038/onc.2016.203.
9. Rigoutsos I, Paranjape AN, et al. N-BLR, a primate-specific non-coding transcript leads to colorectal cancer invasion and migration. Genome Biol 2017;18: 98. doi:10.1186/s13059-017-1224-0.
10. Gril B, Paranjape AN (equal contribution), et al. Reactive astrocytic S1P3 signaling modulates the blood-tumor barrier in brain metastases. Nat Commun 2018;9:2705, doi:10.1038/s41467-018-05030-w.
11. Soundararajan R, Paranjape AN, Maity S, Aparicio A, Mani SA. EMT, stemness and tumor plasticity in aggressive variant neuroendocrine prostate cancers. Biochim Biophys Acta Rev Cancer 2018;1870:229-238. doi:10.1016/j.bbcan.2018.06.006.
12. Khan I, Gril B, Paranjape AN , et al. Albumin as a probe for clathrin-independent endocytosis and transcytosis into experimental brain metastases of breast cancer. bioRxiv 2022; (pre-print). doi: https://doi.org/10.1101/2022.08.09.503253.
