Faculty & Staff

Faculty & Staff

Jianjun Wang, PhD

Research Assistant Professor of Medicine, University of Pittsburgh School of Medicine
UPMC Heart and Vascular Institute

Faculty Member

Peer Reviewed Articles

1. Kamalesh S, Tan P, Wang J, Lee T, Kang ET, Wang CH. Biocompatibility of electroactive polymers in tissues. J Biomed Mater Res 2000;52(3):467-478.

2. Wong HM, Wang J, Wang CH. In vitro sustained release of human immunoglobulin G from biodegradable microspheres. Ind and Eng Chem Res 2001;40:933-948.

3. Lee TH, Wang J, Wang CH. Controlled release of Etanidazole from double-walled biodegradable microspheres. J Contr Release 2002;83:437-452.

4. Yip EY, Wang J, Wang CH. Fabrication of sustained release systems for highly water soluble drugs: irradiation and degradation studies. Biomaterials 2003;24:1977-1987.

5. Wang J, Ng CW, Win KY, Shoemakers P, Feng SS, Wang CH. Release of paclitaxel from polylactide-co-glycolide (PLGA) microparticles and discs under irradiation. J Microencapsulation 2003;20:317-327.

6. Wang J, Chua KM, Wang CH. Stabilization and encapsulation of human immunoglobulin G into biodegradable microspheres. J Colloids Interface Sci 2004;271:92-101.

7. Villanueva FS, Lu E, Bowry S, Kilic S, Tom E, Wang J, Gretton J, Pacella JJ, Wagner WR.  Myocardial ischemic memory imaging using molecular echocardiography. Circulation 2007;115:345-352.

8. Toma C, Fisher A, Wang J, Chen X, Grata M, Leeman J, Winston B, Kaya M, Fu H, Lavery L, Fischer D, Wagner WR, Villanueva FS.  Vascular endoluminal delivery of mesenchymal stem cells using acoustic radiation force. Tissue Eng J Part A 2011;17(9-10):1457-1464.

9. Kaya M, Toma C, Wang J, Grata M, Fu H, Villanueva FS, Chen X. Acoustic radiation force for vascular cell therapy: Theory and in vitro validation. Ultrasound Med Biol 2012;38:1989-2012.

10. Chen X, Wang J, Wang J, Versluis M, de Jong N, Villanueva FS. Ultra-fast brightfield and fluorescence imaging of the dynamics of micrometer sized objects. Rev Sci Instrum 2013;84:063701;1-13.

11. Leng X, Wang J, Carson A, Chen X, Fu H, Ottoboni S, Wagner WR, Villanueva FS. Ultrasound detection of myocardial ischemic memory using an E-selectin targeting peptide amenable to human application. J Molecular Imaging 2014;16:1-9.

12. Chen X, Leeman JE, Wang J, Pacella JJ, Villanueva FS. New insights into mechanisms of sonothrombolysis using ultra-high speed imaging. Ultrasound Med Biol 2014;40:258-262.

13. Chen X, Wang J, Pacella JJ, Villanueva FS. The dynamic behavior of microbubbles during long ultrasound tone-burst excitation: mechanistic insights into ultrasound-microbubble mediated therapeutics using high-speed imaging and cavitation detection. Ultrasound Med Biol 2016;42(2):528-538.

14. Yu FTH, Chen X, Wang J, Qin B, Panday R, Villanueva FS. Low intensity ultrasound mediated liposomal doxorubicin delivery using polymer microbubbles. Mol Pharmaceutics 2016;13(1):55-64.

15. Wang J, Qin B, Chen X, Wagner WR, Villanueva FS. Ultrasound molecular imaging of angiogenesis using vascular endothelial growth factor-conjugated microbubbles. Mol Pharmaceutics 2017; (in press). Epub 2017 Feb 6. doi: 10.1021/acs.molpharmaceut.6b01033.



1. Toma C, Villanueva FS, Wagner WR, Lee JS, Wang J, Chen X, Fischer A. Directed cell-based therapy using microbubble tagged cells. US Patent 8,460,269 issued June 11, 2013.

2. Wang J, Villanueva FS, Chen X, Fisher A, Wagner WR. Intracellular microbubble for imaging an anatomical site. US Patent 8,940,277 issued January 27, 2015.