Faculty & Staff
Jianhui Zhu, PhD
Research Assistant Professor of Medicine, University of Pittsburgh School of Medicine
UPMC Heart and Vascular Institute
- University of Pittsburgh
- Scaife Hall S950
- 3550 Terrace Street
- Pittsburgh, PA 15213
- 412-648-9721
- jiz19@pitt.edu
Peer Reviewed Articles
1. Zhu JH, Dagda RK, Chu CT. Monitoring mitophagy in neuronal cell cultures. Methods in Mol Biol 2011;793:325-39.
2. Hu XM, Weng ZF, Chu CT, Zhang LL, Cao GD, GaoYQ, Signore A, Zhu JH, Hastings T, Greenamy JT, Chen J. Peroxiredoxin-2 protects against 6-hydroxydopamine-induced dopaminergic neurodegeneration via attenuation of the ASK1 signaling cascade. J Neurosci 2011;5:31(1):247-61.
3. Gusdon AM, Zhu JH, Van Houten B, Chu CT. ATP13A2 regulates mitochondrial bioenergetics through macroautophagy. Neurobiol Dis 2012;45:962-972. doi:10.1016/j.nbd.2011.12.015.
4. Zhu JH, Gusdon AM, Cimen H, Van Houten B, Koc E, Chu CT. Impaired mitochondrial biogenesis contributes to depletion of functional mitochondria in chronic MPP+ toxicity: dual roles for ERK1/2. Cell Death Dis 2013;3:e312. doi:10.1038/cddis.2012.46.
5. Zhu JH, Wang KZQ, Chu CT. After the banquet: Mitochondrial biogenesis, mitophagy and cell survival. Autophagy 2013;9 (9): 1-14.
6. Chu CT, Ji J, Dagda RK, Jiang JF, Tyurina YY, Kapralov AA, Tyurin VA, Yanamala N, Shrivastava IH, Mohammadyani D, Wang KZQ, Zhu JH, Klein-Seetharaman J,Balasubramanian K, Amoscato AA, Borisenko G ,Huang ZT, Gusdon A, Cheikhi A, Steer EK, Wang R, Baty C, Watkins S, Bahar I, Bayır H and Kagan VE. Cardiolipin externalization to the outer mitochondrial membrane acts as an elimination signal for mitophagy in mammalian cells. Nat Cell Biol 2013;15(10): 1197-1205.
7. Dagda RK, Pien I, Wang R, Zhu JH, Wang KZQ, Callio J, Chu CT. Beyond the mitochondrian: cytosolic PINK1 remodels dendrites through PKA in neurons. J Neurochem 2014;128(6):864-77.
8. Wang KZ, Zhu JH, Dagda RK, Uechi G, Cherra SG 3rd, Gusdon AM, Balasubramani M, Chu CT. ERK-mediated phosphorylation of TFAM downregulates mitochondrial transcription. Mitochondrion 2014;17:132-140.
