Post Doctoral Fellows
Jonathan Kopechek, PhD
Post-doctoral Fellow, University of Pittsburgh UPMC Heart and Vascular Institute
- 412.648.8475
- kopechekja@upmc.edu
Education
BS, Electrical & Computer Engineering, The Ohio State University, 2006
PhD, Biomedical Engineering, University of Cincinnati, 2011
Research Interests
Dr. Kopechek’s research interests are focused on developing novel image-guided therapies utilizing ultrasound-mediated delivery of molecular therapeutics for treatment of cancer and cardiovascular diseases. His research efforts at the Center for Ultrasound Molecular Imaging and Therapeutics are centered on the translational development of ultrasound and microbubble-based therapies for delivery of small molecular weight nucleic acids. He previously studied ultrasound and microbubble-mediated delivery of a transcription factor decoy to knock down STAT3 signaling and inhibit tumor growth in murine squamous cell carcinomas. Dr. Kopechek is currently funded through a Ruth L. Kirschstein National Research Service Award (NIH/F32) Postdoctoral Fellowship to develop an ultrasound and microbubble platform for therapeutic delivery of microRNA inhibitors to the heart. The goal of this project is to suppress left ventricular hypertrophy and inhibit progression to heart failure.
